Linalool occurs in over 200 species of plants, commonly in lavender, rose, and citrus. This terpene usually constitutes 5% or less of cannabis essential oil and has pleasant floral notes. Nevertheless, Linalool exhibits strong biological activity. Research studies showed that Linalool is one of the most powerful sedating terpene upon inhalation in mice.

Medicinal qualities:


Effects of inhaled Linalool in anxiety, social interaction, and aggressive behavior in mice:

Linck, V. M., da Silva, A. L., Figueiró, M., Caramão, E. B., Moreno, P. R. H., & Elisabetsky, E. (2010)

Linalool Odor-Induced Anxiolytic Effects in Mice.

Harada, H., Kashiwadani, H., Kanmura, Y., & Kuwaki, T. (2018)

Reduces opioids dependency

Effect of Linalool on morphine tolerance and dependence in mice.

Hosseinzadeh, H., Imenshahidi, M., Hosseini, M., & Razavi, B. M. (2012)


(-)-Linalool produces antinociception in two experimental models of pain.

Peana, A. T., D’Aquila, P. S., Chessa, M. L., Moretti, M. D., Serra, G., & Pippia, P. (2003)


Antidepressant activity of Litsea glaucescens essential oil: identification of β-pinene and Linalool as active principles.

Guzmán-Gutiérrez, S. L., Gómez-Cansino, R., García-Zebadúa, J. C., Jiménez-Pérez, N. C., & Reyes-Chilpa, R. (2012)


Inhaled linalool-induced sedation in mice.

De Moura Linck, V., da Silva, A. L., Figueiró, M., Piato, Â. L., Herrmann, A. P., Dupont Birck, F., Caramão, E. B., Nunes, D. S., Moreno, P. R. H., & Elisabetsky, E. (2009)


Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils:

Peana, A. T., D’Aquila, P. S., Panin, F., Serra, G., Pippia, P., & Moretti, M. D. (2002)


Anticonvulsant properties of Linalool in glutamate-related seizure models:

Elisabetsky, E., Brum, L. F., & Souza, D. O. (1999)



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